From site activation to close-out, Medwave handles clinical monitoring and site management across neuro-oncology and radiation oncology trials. We know these indications, the sites that run them, and what it takes to keep a study on track. We also support partner organisations with knowledge transfer for CRAs stepping into these indications for the first time.
Site Set-up & IRB Coordination
End-to-end site activation support, including site feasibility and selection, contract negotiations, ethics committee and IRB submissions, and regulatory documentation. Everything in place before the first patient arrives.
Neuro-oncology Monitoring
A dedicated group of CRAs with hands-on experience in neuro-oncology and radiation oncology, across both drug and device trials. They understand what these indications demand and how to monitor them accordingly.
CRA Training & Development
Hands-on knowledge transfer for CRAs from partner organisations working in neuro-oncology for the first time. We share practical know-how on PFS endpoints, RANO assessment criteria, pseudoprogression, and the day-to-day monitoring realities of GBM and other brain tumour trials, learnt from years on the ground in these studies.
Remote Monitoring
Medwave supports cost-efficient remote monitoring by applying automated consistency checks to exported study data. Database exports are screened for clinically relevant discrepancies, including out-of-range values, conflicting assessments, unusual adverse event patterns, and inconsistencies in AE severity, seriousness or relationship classifications.
By converting study data into focused review outputs, Medwave helps CRAs and medical reviewers concentrate on the areas where follow-up is truly needed. This enables sponsors to maintain essential monitoring oversight while reducing reliance on frequent on-site visits, helping control study costs without compromising data quality or patient safety oversight.