Oncology Imaging Services
Medwave offers full central imaging workflow management for oncology clinical trials with imaging-derived endpoints requiring central review. Our integrated approach connects EDC, imaging upload, and central review systems to minimise data redundancy and streamline reconciliation.
Central Review Concepts
Remote Radiology Review
Blinded central remote radiology review by qualified radiologists, independent from site assessments.
Review with Adjudication
Central radiology review with a formal adjudication process when readers disagree on response assessments.
Risk-Based Review
Targeted central review based on risk profile, focusing resources where imaging discrepancies are most likely.
Site Reading
Sites connect to read software with predefined response criteria and structured data capture for standardised assessments.
Tumor Response Criteria Supported
Solid Tumors
WHO, RECIST 1.0 & 1.1, mRECIST HCC, irRC, irRECIST 1.1, Choi
Haematological
Cheson, Lugano classification, LyRIC, PCWG2
CNS Tumors
RANO, iRANO including modified RANO with parametric maps to differentiate pseudo-progression from true progression.
Diagnostic Efficacy Assessments
Hot-spot Analysis
Lesion identification and hot-spot analysis for investigational radionuclides.
Lesion Matching
Tumour contrast assessments and systematic lesion matching across time points.
Sensitivity & Specificity
Standard of truth assessments with sensitivity and specificity analysis.